Clinical Characteristics of COVID-19 Patients at the San Estanislao District Hospital
DOI:
https://doi.org/10.30545/scientiamericana.2024.set-dic.2Keywords:
COVID-19, clinical characteristics, ParaguayAbstract
Introduction: The study focused on describing the clinical characteristics of COVID-19 patients treated at the San Estanislao District Hospital between February 2020 and February 2021, in the context of an overwhelmed healthcare system due to the pandemic. Objective: To determine the clinical characteristics of patients diagnosed with COVID-19 at the San Estanislao District Hospital, evaluating sociodemographic, clinical, and risk factors. Methodology: An observational, descriptive, and retrospective study was conducted with 512 patients diagnosed using PCR and antigen tests. Demographic, clinical, and comorbidity variables were analyzed. Results: 52% of the patients were women and 48% were men, predominantly in the age groups of 21-40 years. The most frequent symptoms were fever and sore throat (26%) and cough with rhinorrhea (23%), while 18% were asymptomatic. Only 18% had comorbidities, with hypertension (7%) and diabetes (4%) being the most common. Hospitalization was required for 97% of the patients, and the mortality rate was low (3%). Conclusions: The results highlight the low prevalence of severe comorbidities and the need to adapt management protocols to the specific characteristics of the treated population. The observed low mortality emphasizes the importance of early and effective management in resource-limited settings, providing valuable information for future prevention and treatment strategies.
Downloads
References
1. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med [Internet]. 2020 [Citado 24 Set. 2024] ;382(18):1708- 1720. Disponible en: http://dx.doi.org/10.1056/ NEJMoa2002032 2.
2. Ríos-González CM, Rolón Ruiz Diaz A, Espinola-Canata M, Battaglia A, Mayeregger E. Comportamiento clínico y epidemiológico de pacientes internados por COVID-19 en un Hospital de Contingencia para COVID-19 de Paraguay, 2020. Rev Salud Publica Parag [Internet]. 2021 [Citado 24 Set. 2024] ;11(1):62- 66. Disponible en: http://dx.doi.org/10.18004/ rspp.2021.junio.62 3.
3. Montiel D, Torres E, Acosta A, Sobarzo P, Pérez H, Ávalos D, et al. Características clínicas, laboratoriales y predictores de mortalidad de pacientes con COVID-19 internados en el Hospital Nacional. Rev Cient Cienc Salud [Internet]. 2021 [Citado 24 Set. 2024];3(1):26-37. Disponible en: https://doi.org/10.53732/rccsalud/03.01.2021.26 4.
4. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA [Internet]. 2020 [Citado 24 Set. 2024] ;323(20):2052-2059. Disponible en: https://doi. org/10.1001/jama.2020.6775 5.
5. Docherty AB, Harrison EM, Green CA, Hardwick HE, Pius R, Norman L, et al. Features of 20,133 UK patients in hospital with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ [Internet]. 2020 [Citado 24 Set. 2024] ;369:m1985. Disponible en: https://doi.org/10.1136/bmj.m1985
6. Casas-Rojo JM, Antón-Santos JM, Millán-NúñezCortés J, Lumbreras-Bermejo C, Ramos-Rincón JM, Roy-Vallejo E, et al. Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del registro SEMI-COVID-19. Rev Clin Esp [Internet]. 2020 [Citado 24 Set. 2024] ;220:480–494. Disponible en: https://doi. org/10.1016/j.rce.2020.07.003
7. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA [Internet]. 2020 [Citado 24 Set. 2024] ;323(16):1574-1581. Disponible en: https://doi.org/10.1001/jama.2021.5060
8. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost [Internet]. 2020 [Citado 24 Set. 2024] ;18(4):844-847. Disponible en: https://doi.org/10.1111/jth.14768.
9. Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, et al. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J [Internet]. 2020 [Citado 24 Set. 2024] ;55(5):2000547. Disponible en: https:// doi.org/10.1183/13993003.00547-2020
10. Klein SL, Pekosz A, Park HS, et al. Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population. J Clin Invest [Internet]. 2020 [Citado 24 Set. 2024] ;130(11):6141-6150. Disponible en: https://doi.org/10.1172/JCI142004
11. Peckham H, de Gruijter NM, Raine C, et al. Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission. Nat Commun [Internet]. 2020 [Citado 24 Set. 2024] ;11(1):6317. Disponible en: https://doi. org/10.1038/s41467-020-19741-6
12. Pusineri Escobar Paola, González-Gómez Manuel, Barrios Iván, Torales Julio. Mortalidad en adultos con COVID-19: experiencia de la Unidad de Cuidados Intensivos de un Hospital de Tercer Nivel de Paraguay. Med Clín Soc [Internet]. 2023 [Citado 24 Set. 2024] ;7(1):5-10. Disponible en: https://doi.org/10.52379/mcs.v7i1.272.
13. Ruiz Cantero MT. Las estadísticas sanitarias y la invisibilidad por sexo y de género durante la epidemia de COVID-19. Gac Sanit [Internet]. 2021 [Citado 24 Set. 2024] ;35(1):95-98. Disponible en: https://doi.org/10.1016/j.gaceta.2020.04.008
14. Valdez Huarcaya W, Miranda Monzón JA, Napanga Saldaña EO, Driver CR. Impacto de la COVID-19 en la mortalidad en Perú mediante la triangulación de múltiples fuentes de datos. Rev Panam Salud Publica [Internet]. 2022 [Citado 24 Set. 2024] ;46. Disponible en: https://doi. org/10.26633/RPSP.2022.53
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Cinthia Mabel Rojas Patiño, Zulma Cabrera Alfonso, Olga Sosa Aquino, Sandra Gonzalez Bogarin, Leslie Duarte Pedrozo, Vanessa Mabel Diaz Bareiro, Harumi Asai Vera
This work is licensed under a Creative Commons Attribution 4.0 International License.
